Exclude domains/senders to Eset Mail Security approvedsenders file

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Open Notepad.exe as administrator.

Navigate to:
Windows Server 2008/R2 – %\Program Data\ESET\ESET Mail Security \ServerAntispam\
Windows Server 2000/2003 – %\Documents and Settings\All Users\Application Data\ESET \ESET Mail Security\MailServer

Open file: approvedsenders

Add email addresses or domains.

Source: Wilders Security

Source: EMSX 4 User Guide